Pepperoni and Beef Casserole

Pepperoni and Beef Casserole


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A simple yet delicious casserole reminiscent of cheesy pizza. This quick and easy weeknight meal is sure to be a crowd pleaser every time.

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Chicago, IL

Time needed

10 min preparation + 40 min cooking

Serving Size / Yield

6 servings


  • 1 lb ground round
  • 1/2 lb pepperoni
  • 1/2 cup chopped onion
  • 1/2 teaspoon ground allspice
  • 1/2 teaspoon salt
  • 1/2 teaspoon pepper
  • 1/2 pound shredded mozzarella
  • 1/4 to 1/2 pound ricotta cheese
  • 3 cups meatless spaghetti sauce, homemade or jarred

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Heat oven to 350 degrees.
Cook and stir beef and pepperoni in a large skillet. Add onion, allspice, salt, and pepper. Cook until onion is softened.
In a greased 2-1/4 quart casserole dish, layer the noodles, meat mixture, cheeses, and sauce.
Repeat layers once or twice, ending with a sprinkling of mozzarella cheese.
Bake for about 35-40 minutes or until bubbly.
Let casserole cool for about 5 minutes

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